Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PEPD | P12955 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | BLM | P54132 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3995569 | 0.83 | ESR1 (0.55) | CA2ALDH1A1GAACA1BLM | |
| SCHEMBL11647073 | 0.83 | CA1 (0.41) | CA2ALDH1A1CA1MAPTHIF1A | |
| SCHEMBL4572857 | 0.81 | CA12 (0.53) | CA2ALDH1A1GAACA1MAPT | |
| SCHEMBL5518500 | 0.81 | ALDH1A1 (0.55) | CA2ALDH1A1GAACA1MEN1 | |
| Hydrochloric Acid SCHEMBL4804173 | 0.81 | ESR1 (0.54) | CA2GAACA1BLMMEN1 | |
| SCHEMBL4395547 | 0.81 | NPC1 (0.55) | CA2ALDH1A1GAACA1MEN1 | |
| SCHEMBL7445665 | 0.81 | MEN1 (0.50) | CA2ALDH1A1GAACA1MEN1 | |
| SCHEMBL22354 | 0.80 | CYP1A1 (0.52) | PEPDCA2ALDH1A1GAAMAPK1 | |
| SCHEMBL9745051 | 0.80 | CYP1A1 (0.52) | PEPDCA2ALDH1A1GAAMAPK1 | |
| Hydrochloric Acid SCHEMBL11326485 | 0.80 | CYP1A1 (0.52) | PEPDCA2ALDH1A1GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2723882-B1 | PROCESS FOR PREPARING 3'-THIOSUBSTITUTED CEPHALOSPORINS EMPLOYING A PENICILLIN G ACYLASE | CENTRIENT PHARMACEUTICALS NETHERLANDS B V (NL) | 2019-05-01 | — | — | EP | claimed |
| US-20150112057-A1 | NOVEL CRYSTALLINE CEFOPERAZONE INTERMEDIATE | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2015-04-23 | — | — | US | claimed |
| EP-2723881-A2 | NOVEL CRYSTALLINE CEFOPERAZONE INTERMEDIATE | DSM Sinochem Pharmaceuticals Netherlands B.V. (NL) | 2014-04-30 | — | — | EP | claimed |
| EP-2723882-A1 | PROCESS FOR PREPARING 3'-THIOSUBSTITUTED CEPHALOSPORINS EMPLOYING A PENICILLIN G ACYLASE | DSM Sinochem Pharmaceuticals Netherlands B.V. (NL) | 2014-04-30 | — | — | EP | claimed |
| WO-2012175585-A1 | PROCESS FOR PREPARING 3'-THIOSUBSTITUTED CEPHALOSPORINS EMPLOYING A PENICILLIN G ACYLASE | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2012-12-27 | — | — | WO | claimed |
| WO-2012175587-A2 | NOVEL CRYSTALLINE CEFOPERAZONE INTERMEDIATE | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2012-12-27 | — | — | WO | claimed |
| EP-1603549-A2 | IMPROVED BIOAVAILABILITY AND IMPROVED DELIVERY OF ACIDIC PHARMACEUTICAL DRUGS | Yu, Ruey J., Dr. (US) | 2005-12-14 | — | — | EP | claimed |
| US-6824786-B2 | TOPICAL APPLYING COSMETIC | YU RUEY J (US) | 2004-11-30 | — | — | US | claimed |
| US-20040220264-A1 | Bioavailability and improved delivery of acidic pharmaceutical drugs | YU RUEY J | 2004-11-04 | — | — | US | claimed |
| WO-2004082628-A2 | IMPROVED BIOAVAILABILITY AND IMPROVED DELIVERY OF ACIDIC PHARMACEUTICAL DRUGS | YU RUEY J (US) | 2004-09-30 | — | — | WO | claimed |
| WO-2003045338-A1 | COMPOSITIONS COMPRISING PHENYL-GLYCINE DERIVATIVES | YU RUEY J (US) | 2003-06-05 | — | — | WO | claimed |
| EP-0865443-B1 | PROCESS FOR THE PREPARATION OF AN ANTIBIOTIC | DSM NV (NL) | 2003-03-19 | — | — | EP | claimed |
| WO-2002074266-A2 | METHOD AND COMPOSITION FOR THE GRADUAL PERMANENT COLORING OF HAIR | UNILEVER PLC (GB) | 2002-09-26 | — | — | WO | claimed |
| EP-0960945-B1 | Enzymatic process for producing beta-lactam antibiotics involving product recovery at pH 1 in the presence of immobilized penicillin amidase | UNIFAR KIMYA SANAYII VE TICARE (TR) | 2002-09-04 | — | — | EP | claimed |
| EP-1019363-B1 | PROCESS FOR THE PREPARATION OF AN INORGANIC SALT OF AN OPTICALLY ACTIVE PHENYLGLYCINE DERIVATIVE | DSM NV (NL) | 2002-08-28 | — | — | EP | claimed |
| US-6218138-B1 | REACTING AMINO-BETA-LACTAM COMPONENT AND CORRESPONDING AMINO-GROUP CONTAINING ACYLATING SIDE CHAIN COMPONENT IN PRESENCE OF BIOCATALYSTTO FORM ANTIBIOTIC, SOLUBILIZING BY ADDING ACID WHICH DEACTIVATES ENZYME; ENZYME IS REUSEDENZYME | UNIFAR KIMYA SANAYI VE TICARET A.S. (TM) | 2001-04-17 | — | — | US | claimed |
| EP-0960945-A2 | Enzymatic process for producing beta-lactam antibiotics involving product recovery at pH 1 in the presence of immobilized penicillin amidase | Unifar Kimya Sanayii ve Ticaret A.S (TR) | 1999-12-01 | — | — | EP | claimed |
| US-5306826-A | Mixing mixture of Schiff bases of amides or amides and aldehyde, solvent, optically active acid, water to form salt, separating diastereomers, converting salt to amide | STAMICARBON B.V. (NL) | 1994-04-26 | — | — | US | claimed |
| EP-0442584-B1 | Process for the preparation of an optically active amino acid amide | DSM NV (NL) | 1993-11-10 | — | — | EP | claimed |
| EP-0442584-A1 | Process for the preparation of an optically active amino acid amide | DSM N.V. (NL) | 1991-08-21 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150112057-A1 | NOVEL CRYSTALLINE CEFOPERAZONE INTERMEDIATE | CPN1, PEPD, GLO1 | PEPD 2/4885CA2 2272/4885ALDH1A1 1421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.