Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29758132 | 1.00 | MAPT (0.65) | MAPTKMT2AALDH1A1MEN1POLB | |
| SCHEMBL16168691 | 0.82 | POLB (0.65) | MAPTKMT2AALDH1A1MEN1POLB | |
| SCHEMBL14322049 | 0.80 | MAPT (0.55) | MAPTKMT2AALDH1A1MEN1POLB | |
| SCHEMBL14321628 | 0.79 | MAPT (0.53) | MAPTKMT2AALDH1A1MEN1POLB | |
| SCHEMBL22636765 | 0.79 | GAA (0.53) | MAPTKMT2AALDH1A1MEN1POLB | |
| SCHEMBL10066581 | 0.79 | KMT2A (0.53) | MAPTKMT2AALDH1A1MEN1POLB | |
| SCHEMBL299335 | 0.79 | MAPT (0.65) | MAPTKMT2AALDH1A1MEN1POLB | |
| SCHEMBL10022433 | 0.79 | KMT2A (0.53) | MAPTKMT2AALDH1A1MEN1POLB | |
| SCHEMBL4455066 | 0.78 | KMT2A (0.51) | MAPTKMT2AALDH1A1MEN1POLB | |
| SCHEMBL31009041 | 0.78 | KMT2A (0.51) | MAPTKMT2AALDH1A1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728917-B | Oxamide derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-114728917-A | Oxamide derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-07-08 | — | — | CN | disclosed |
| WO-2021110076-A1 | OXAMIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 深圳信立泰药业股份有限公司 | 2021-06-10 | — | — | WO | disclosed |
| WO-2002064211-A1 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2002-08-22 | — | — | WO | disclosed |