Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 6/20 | 0.38 |
| ▸ | CTSK | P43235 | 5/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPR3 | P17342 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10660301 | 0.88 | CTSS (0.49) | CTSSCTSKITGA4ITGB7 | |
| SCHEMBL7807672 | 0.86 | ITGA4 (0.50) | CTSSCTSKITGA4ITGB7CTSL | |
| SCHEMBL12379269 | 0.80 | ATM (0.46) | POLB | |
| Hydrochloric Acid SCHEMBL6140899 | 0.79 | ATM (0.44) | POLB | |
| SCHEMBL5887853 | 0.78 | LY96 (0.47) | CTSSCTSKITGA4ITGB7KLK5 | |
| SCHEMBL5887857 | 0.78 | LY96 (0.47) | CTSSCTSKITGA4ITGB7KLK5 | |
| Hydrochloric Acid SCHEMBL6140896 | 0.77 | ATM (0.43) | POLB | |
| SCHEMBL10604728 | 0.76 | CTSS (0.48) | CTSSCTSKITGA4ITGB7ACE | |
| SCHEMBL27494388 | 0.76 | CTSS (0.48) | CTSSCTSKITGA4ITGB7ACE | |
| SCHEMBL19354815 | 0.76 | CTSS (0.53) | CTSSCTSKITGA4ITGB7POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0677043-A4 | — | — | 1995-11-22 | — | — | EP | disclosed |
| EP-0677043-A1 | PLATELET AGGREGATION INHIBITING COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-18 | — | — | EP | disclosed |
| WO-1994014775-A1 | PLATELET AGGREGATION INHIBITING COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |