Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.64 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.64 |
| ▸ | FPR2 | P25090 | 5/20 | 0.40 |
| ▸ | FPR1 | P21462 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7454539 | 0.99 | ITGB3 (0.63) | ITGB3ITGA2BFPR2FPR1HDAC6 | |
| SCHEMBL7444870 | 0.91 | ITGB3 (0.68) | ITGB3ITGA2BFPR2FPR1HDAC6 | |
| SCHEMBL7446802 | 0.90 | ITGB3 (0.66) | ITGB3ITGA2BFPR2FPR1HDAC6 | |
| SCHEMBL7448793 | 0.90 | ITGB3 (0.78) | ITGB3ITGA2BFPR2FPR1 | |
| SCHEMBL7446009 | 0.89 | ITGB3 (0.67) | ITGB3ITGA2BFPR2FPR1HDAC6 | |
| Hydrochloric Acid SCHEMBL7448776 | 0.89 | ITGB3 (0.77) | ITGB3ITGA2BFPR2FPR1 | |
| Hydrochloric Acid SCHEMBL7445993 | 0.89 | ITGB3 (0.66) | ITGB3ITGA2BFPR2FPR1HDAC6 | |
| SCHEMBL7447973 | 0.88 | ITGB3 (0.81) | ITGB3ITGA2BFPR2FPR1HDAC6 | |
| SCHEMBL7455251 | 0.88 | ITGB3 (0.61) | ITGB3ITGA2BFPR2FPR1HDAC6 | |
| SCHEMBL8093675 | 0.87 | ITGB3 (0.64) | ITGB3ITGA2BFPR2FPR1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025358-A | Double prodrugs of potent GP IIb/IIIa antagonists | G. D. SEARLE & CO. (US) | 2000-02-15 | — | — | US | claimed |
| WO-1999064397-A1 | DOUBLE PRODRUGS OF POTENT GPIIb/IIIa ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-12-16 | — | — | WO | claimed |
| US-6025358-A | Double prodrugs of potent GP IIb/IIIa antagonists | G. D. SEARLE & CO. (US) | 2000-02-15 | — | — | US | disclosed |
| WO-1999064397-A1 | DOUBLE PRODRUGS OF POTENT GPIIb/IIIa ANTAGONISTS | G.D. SEARLE & CO. (US) | 1999-12-16 | — | — | WO | disclosed |