Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.64 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.64 |
| ▸ | FPR2 | P25090 | 6/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.39 |
| ▸ | FPR1 | P21462 | 2/20 | 0.39 |
| ▸ | CCKBR | P32239 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444870 | 0.91 | ITGB3 (0.68) | ITGB3ITGA2BFPR2HDAC1HDAC8 | |
| SCHEMBL8109424 | 0.90 | ITGB3 (0.66) | ITGB3ITGA2BFPR2HDAC1HDAC8 | |
| SCHEMBL7449217 | 0.89 | ITGB3 (0.67) | ITGB3ITGA2BFPR2HDAC1HDAC8 | |
| SCHEMBL7447973 | 0.88 | ITGB3 (0.81) | ITGB3ITGA2BFPR2HDAC1HDAC8 | |
| SCHEMBL8103425 | 0.88 | ITGB3 (0.61) | ITGB3ITGA2BFPR2HDAC1HDAC8 | |
| Acetic Acid SCHEMBL8109437 | 0.88 | ITGB3 (0.75) | ITGB3ITGA2BFPR2FPR1 | |
| Hydrochloric Acid SCHEMBL7447955 | 0.87 | ITGB3 (0.80) | ITGB3ITGA2BFPR2HDAC1HDAC8 | |
| SCHEMBL7445984 | 0.87 | ITGB3 (0.64) | ITGB3ITGA2BFPR2HDAC1HDAC8 | |
| Hydrochloric Acid SCHEMBL7454539 | 0.86 | ITGB3 (0.63) | ITGB3ITGA2BFPR2HDAC1HDAC8 | |
| SCHEMBL7446963 | 0.86 | ITGB3 (0.70) | ITGB3ITGA2BFPR2HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025358-A | Double prodrugs of potent GP IIb/IIIa antagonists | G. D. SEARLE & CO. (US) | 2000-02-15 | — | — | US | claimed |
| US-6025358-A | Double prodrugs of potent GP IIb/IIIa antagonists | G. D. SEARLE & CO. (US) | 2000-02-15 | — | — | US | disclosed |