Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.56 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 6/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.50 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961013 | 0.90 | F2 (0.58) | F2ITGA4ESR1ESR2UBE2N | |
| SCHEMBL7961018 | 0.90 | F2 (0.58) | F2ITGA4ESR1ESR2UBE2N | |
| SCHEMBL6596926 | 0.88 | ITGA4 (0.69) | F2ITGA4ESR1ESR2LTA4H | |
| SCHEMBL6596335 | 0.87 | ITGA4 (0.68) | F2ITGA4ESR1ESR2LTA4H | |
| SCHEMBL6175191 | 0.87 | F2 (0.59) | F2ITGA4ESR1ESR2UBE2N | |
| SCHEMBL6175195 | 0.87 | F2 (0.59) | F2ITGA4ESR1ESR2UBE2N | |
| SCHEMBL6172878 | 0.85 | ESR1 (0.66) | F2ITGA4ESR1ESR2UBE2N | |
| SCHEMBL6595626 | 0.85 | F2 (0.59) | F2ITGA4ESR1ESR2UBE2N | |
| SCHEMBL7446115 | 0.84 | F2 (0.56) | F2ITGA4ESR1ESR2UBE2N | |
| SCHEMBL6595837 | 0.84 | F2 (0.76) | F2ITGA4ESR1ESR2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863755-A4 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 1999-01-20 | — | — | EP | disclosed |
| EP-0863755-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997025033-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |