⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL66215 | 1.00 | — | — | |
| SCHEMBL65171 | 0.70 | — | — | |
| SCHEMBL2121805 | 0.70 | — | — | |
| SCHEMBL21646359 | 0.69 | TBXAS1 (0.40) | — | |
| SCHEMBL23697848 | 0.69 | TBXAS1 (0.40) | — | |
| SCHEMBL29974816 | 0.69 | ALOX15 (0.48) | — | |
| SCHEMBL28486243 | 0.69 | ALOX15 (0.48) | — | |
| SCHEMBL869469 | 0.68 | — | — | |
| SCHEMBL3262556 | 0.67 | — | — | |
| SCHEMBL13260083 | 0.67 | TBXAS1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0896578-A1 | NOVEL IMIDAZO 1,5-c]QUINAZOLINES; A NEW CLASS OF GABA BRAIN RECEPTOR LIGANDS | NEUROGEN CORPORATION (US) | 1999-02-17 | — | — | EP | disclosed |
| WO-1997033889-A1 | NOVEL IMIDAZO[1,5-c]QUINAZOLINES; A NEW CLASS OF GABA BRAIN RECEPTOR LIGANDS | NEUROGEN CORPORATION (US) | 1997-09-18 | — | — | WO | disclosed |