Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.56 |
| ▸ | CYP2J2 | P51589 | 5/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10557081 | 0.91 | PAX8 (0.60) | PAX8CYP2J2KCNH2HTR1AHTR7 | |
| SCHEMBL10558297 | 0.85 | PAX8 (0.54) | PAX8CYP2J2KCNH2MEN1HRH1 | |
| SCHEMBL9786892 | 0.84 | CYP2J2 (0.59) | PAX8CYP2J2KCNH2MEN1HRH1 | |
| SCHEMBL7433635 | 0.84 | ABCB11 (0.49) | PAX8CYP2J2KCNH2HTR1AHRH1 | |
| SCHEMBL7429940 | 0.84 | PAX8 (0.49) | PAX8KCNH2HTR1AKDM4EHRH1 | |
| SCHEMBL7430626 | 0.84 | ABCB11 (0.51) | PAX8CYP2J2KCNH2HTR1AHRH1 | |
| SCHEMBL7331615 | 0.83 | HRH1 (0.59) | PAX8CYP2J2KCNH2HTR1AMEN1 | |
| Hydrochloric Acid SCHEMBL10459287 | 0.83 | PAX8 (0.48) | PAX8KCNH2HTR1AKDM4EHRH1 | |
| SCHEMBL10461068 | 0.83 | MAPT (0.57) | PAX8CYP2J2KCNH2MEN1HRH1 | |
| SCHEMBL30627531 | 0.83 | ABCB11 (0.62) | PAX8KCNH2HTR1AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070087-A | Aryl(alkyland alkylene)-N-((phenoxy and phenylthio)alkyl) aminoheterocyclics as cardiovascular, anthihistaminic, antisecretory and antiallergy agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1991-12-03 | — | — | US | disclosed |