Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5372095 | 0.81 | MAPT (0.43) | MAPTSIGMAR1 | |
| SCHEMBL9220204 | 0.80 | MAPT (0.39) | MAPTSIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL8832593 | 0.80 | MAPT (0.39) | MAPTSIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL8832969 | 0.80 | MAPT (0.39) | MAPTSIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL27616211 | 0.80 | MAPT (0.60) | MAPTSIGMAR1HRH2 | |
| SCHEMBL19290959 | 0.80 | MAPT (0.60) | MAPTSIGMAR1HRH2 | |
| SCHEMBL14012805 | 0.77 | SIGMAR1 (0.51) | MAPTSIGMAR1 | |
| SCHEMBL15593209 | 0.77 | SIGMAR1 (0.51) | MAPTSIGMAR1 | |
| SCHEMBL14012809 | 0.77 | SIGMAR1 (0.51) | MAPTSIGMAR1 | |
| SCHEMBL28007890 | 0.76 | MAPT (0.41) | MAPTSIGMAR1CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C Research Laboratories (KR) | 1999-06-02 | — | — | EP | disclosed |
| WO-1997045424-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RESEARCH LABORATORIES (KR) | 1997-12-04 | — | — | WO | disclosed |