Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.38 |
| ▸ | BHMT | Q93088 | 3/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.36 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.36 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.36 |
| ▸ | GRM8 | O00222 | 1/20 | 0.36 |
| ▸ | GRM6 | O15303 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alanine SCHEMBL28294968 | 0.88 | ALDH1A1 (0.40) | SLC7A5SLC1A1BHMTSLC1A3SLC1A2 | |
| Alanine SCHEMBL11511190 | 0.88 | ALDH1A1 (0.40) | SLC7A5SLC1A1BHMTSLC1A3SLC1A2 | |
| Sarcosine SCHEMBL2368384 | 0.88 | ALDH1A1 (0.40) | SLC7A5SLC1A1BHMTSLC1A3SLC1A2 | |
| Sarcosine SCHEMBL17258535 | 0.84 | ALDH1A1 (0.38) | SLC7A5SLC1A1BHMTSLC1A3SLC1A2 | |
| Serine SCHEMBL1270313 | 0.84 | SLC7A5 (0.54) | SLC7A5SLC1A1BHMTSLC1A3SLC1A2 | |
| (D)-Serine SCHEMBL2029988 | 0.84 | SLC7A5 (0.54) | SLC7A5SLC1A1BHMTSLC1A3SLC1A2 | |
| Serine SCHEMBL17603642 | 0.84 | SLC7A5 (0.54) | SLC7A5SLC1A1BHMTSLC1A3SLC1A2 | |
| Serine SCHEMBL8679969 | 0.84 | SLC7A5 (0.54) | SLC7A5SLC1A1BHMTSLC1A3SLC1A2 | |
| Serine SCHEMBL1270317 | 0.84 | SLC7A5 (0.54) | SLC7A5SLC1A1BHMTSLC1A3SLC1A2 | |
| Serine SCHEMBL9448210 | 0.84 | SLC7A5 (0.54) | SLC7A5SLC1A1BHMTSLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073432-A2 | USE OF GLYCINE SITE AGONISTS OR GLYCINE UPTAKE INHIBITORS FOR TREATING NEUROPSYCHIATRIC DISORDERS | THE GENERAL HOSPITAL CORPORATION (US) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999052519-A2 | METHODS FOR TREATING NEUROPSYCHIATRIC DISORDERS | THE GENERAL HOSPITAL CORPORATION (US) | 1999-10-21 | — | — | WO | disclosed |