Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 15/20 | 0.62 |
| ▸ | ITGB3 | P05106 | 12/20 | 0.62 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.62 |
| ▸ | ITGB1 | P05556 | 7/20 | 0.62 |
| ▸ | ITGA5 | P08648 | 7/20 | 0.62 |
| ▸ | ITGB5 | P18084 | 7/20 | 0.62 |
| ▸ | HPGDS | O60760 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESRRG | P62508 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448307 | 0.87 | ITGB3 (0.58) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL7455544 | 0.83 | ITGAV (0.51) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL7976674 | 0.83 | ITGAV (0.51) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL7455550 | 0.83 | ITGAV (0.51) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL7447358 | 0.82 | ITGAV (0.56) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL7452852 | 0.81 | ITGB3 (0.57) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL6016242 | 0.81 | ITGAV (0.53) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL7455915 | 0.78 | ITGB3 (0.53) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL7962800 | 0.78 | ITGB3 (0.53) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL7448645 | 0.78 | ITGB3 (0.59) | ITGAVITGB3ITGA2BITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187825-A1 | THIOPHENE INTEGRIN INHIBITORS | Shire Biochem Inc. (CA) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000075129-A1 | THIOPHENE INTEGRIN INHIBITORS | SHIRE BIOCHEM INC. (CA) | 2000-12-14 | — | — | WO | disclosed |