Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.40 |
| ▸ | FAP | Q12884 | 3/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7485707 | 1.00 | DPP4 (0.46) | DPP4HRH3DPP8FAPDPP9 | |
| SCHEMBL7589304 | 0.97 | DPP4 (0.46) | DPP4HRH3DPP8FAPDPP9 | |
| SCHEMBL7491651 | 0.97 | DPP4 (0.46) | DPP4HRH3DPP8FAPDPP9 | |
| SCHEMBL7491659 | 0.97 | DPP4 (0.46) | DPP4HRH3DPP8FAPDPP9 | |
| SCHEMBL7485307 | 0.83 | HRH3 (0.43) | DPP4HRH3DPP8FAPDPP9 | |
| SCHEMBL7491826 | 0.83 | HRH3 (0.52) | DPP4HRH3 | |
| SCHEMBL7491817 | 0.83 | HRH3 (0.52) | DPP4HRH3 | |
| SCHEMBL7487691 | 0.81 | DPP4 (0.43) | DPP4HRH3DPP8FAPDPP9 | |
| SCHEMBL7487699 | 0.81 | DPP4 (0.43) | DPP4HRH3DPP8FAPDPP9 | |
| SCHEMBL7494232 | 0.80 | HRH3 (0.46) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-B1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RES LAB (KR) | 2002-01-09 | — | — | EP | disclosed |
| US-6201006-B1 | ANTICOAGULANTS | C & C RESEARCH LABORATORIES (KR) | 2001-03-13 | — | — | US | disclosed |
| EP-0918768-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C Research Laboratories (KR) | 1999-06-02 | — | — | EP | disclosed |
| WO-1997045424-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RESEARCH LABORATORIES (KR) | 1997-12-04 | — | — | WO | disclosed |