Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 19/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7491826 | 1.00 | HRH3 (0.52) | HRH3DPP4KCNH2 | |
| SCHEMBL7485078 | 0.87 | HRH3 (0.58) | HRH3KCNH2 | |
| SCHEMBL7491853 | 0.85 | HRH3 (0.52) | HRH3KCNH2 | |
| SCHEMBL7491651 | 0.84 | DPP4 (0.46) | HRH3DPP4 | |
| SCHEMBL7589304 | 0.84 | DPP4 (0.46) | HRH3DPP4 | |
| SCHEMBL7491659 | 0.84 | DPP4 (0.46) | HRH3DPP4 | |
| SCHEMBL7485707 | 0.83 | DPP4 (0.46) | HRH3DPP4 | |
| SCHEMBL7447010 | 0.83 | DPP4 (0.46) | HRH3DPP4 | |
| SCHEMBL7487926 | 0.80 | DPP4 (0.41) | HRH3DPP4 | |
| SCHEMBL7487916 | 0.80 | DPP4 (0.41) | HRH3DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-B1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RES LAB (KR) | 2002-01-09 | — | — | EP | disclosed |
| US-6201006-B1 | ANTICOAGULANTS | C & C RESEARCH LABORATORIES (KR) | 2001-03-13 | — | — | US | disclosed |