Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 10/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | FAP | Q12884 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7491659 | 1.00 | DPP4 (0.46) | DPP4HRH3DPP8PREPFAP | |
| SCHEMBL7491651 | 1.00 | DPP4 (0.46) | DPP4HRH3DPP8PREPFAP | |
| SCHEMBL7485707 | 0.97 | DPP4 (0.46) | DPP4HRH3DPP8PREPFAP | |
| SCHEMBL7447010 | 0.97 | DPP4 (0.46) | DPP4HRH3DPP8PREPFAP | |
| SCHEMBL7491817 | 0.84 | HRH3 (0.52) | DPP4HRH3 | |
| SCHEMBL7491826 | 0.84 | HRH3 (0.52) | DPP4HRH3 | |
| SCHEMBL7494232 | 0.83 | HRH3 (0.46) | HRH3 | |
| SCHEMBL7487691 | 0.82 | DPP4 (0.43) | DPP4HRH3DPP8PREPFAP | |
| SCHEMBL7487699 | 0.82 | DPP4 (0.43) | DPP4HRH3DPP8PREPFAP | |
| SCHEMBL7496749 | 0.81 | DPP4 (0.41) | DPP4HRH3DPP8PREPFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C Research Laboratories (KR) | 1999-06-02 | — | — | EP | disclosed |
| WO-1997045424-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RESEARCH LABORATORIES (KR) | 1997-12-04 | — | — | WO | disclosed |