Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 1/20 | 0.64 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.64 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.64 |
| ▸ | LTA4H | P09960 | 10/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.59 |
| ▸ | HRH1 | P35367 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | DRD5 | P21918 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348634 | 0.93 | PSMB1 (0.55) | PSMB1PSMB5PSMB2LTA4HHRH3 | |
| SCHEMBL7354993 | 0.89 | PSMB1 (0.51) | PSMB1PSMB5PSMB2LTA4HHRH3 | |
| SCHEMBL6969448 | 0.88 | LTA4H (0.50) | PSMB1PSMB5PSMB2LTA4HHRH3 | |
| SCHEMBL6963616 | 0.88 | LTA4H (0.52) | PSMB1PSMB5PSMB2LTA4HHRH3 | |
| SCHEMBL6961322 | 0.88 | HRH1 (0.51) | PSMB1PSMB5PSMB2LTA4HHRH1 | |
| SCHEMBL6956973 | 0.88 | LTA4H (0.49) | PSMB1PSMB5PSMB2LTA4HHRH3 | |
| SCHEMBL6961402 | 0.87 | LTA4H (0.48) | PSMB1PSMB5PSMB2LTA4HHRH3 | |
| SCHEMBL7440783 | 0.87 | LTA4H (0.48) | PSMB1PSMB5PSMB2LTA4HHRH3 | |
| SCHEMBL7349031 | 0.86 | LTA4H (0.49) | PSMB1PSMB5PSMB2LTA4HHRH3 | |
| SCHEMBL6969035 | 0.85 | LTA4H (0.47) | PSMB1PSMB5PSMB2LTA4HHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863755-A4 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 1999-01-20 | — | — | EP | disclosed |
| EP-0863755-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997025033-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |