Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPY1R | P25929 | 1/20 | 0.50 |
| ▸ | NPY2R | P49146 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6859005 | 0.92 | L3MBTL1 (0.68) | L3MBTL1RAB9ANPC1RECQLKMT2A | |
| SCHEMBL29742389 | 0.92 | L3MBTL1 (0.68) | L3MBTL1RAB9ANPC1RECQLKMT2A | |
| SCHEMBL7366723 | 0.85 | L3MBTL1 (0.71) | L3MBTL1RAB9ANPC1RECQLKMT2A | |
| SCHEMBL27520599 | 0.82 | L3MBTL1 (0.64) | L3MBTL1RAB9ANPC1RECQLKMT2A | |
| SCHEMBL2474599 | 0.81 | L3MBTL1 (0.62) | L3MBTL1RAB9ANPC1RECQLKMT2A | |
| SCHEMBL30196559 | 0.81 | L3MBTL1 (0.62) | L3MBTL1RAB9ANPC1RECQLKMT2A | |
| SCHEMBL10453566 | 0.81 | L3MBTL1 (0.62) | L3MBTL1RAB9ANPC1RECQLKMT2A | |
| SCHEMBL20682737 | 0.80 | L3MBTL1 (1.00) | L3MBTL1RAB9ANPC1RECQLKMT2A | |
| SCHEMBL15709049 | 0.80 | L3MBTL1 (1.00) | L3MBTL1RAB9ANPC1RECQLKMT2A | |
| Ammonia Solution, Strong SCHEMBL28331190 | 0.80 | L3MBTL1 (0.60) | L3MBTL1RAB9ANPC1RECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995020576-A1 | 4-(2-(3-ARYLOXY-2-HYDROXYPROPYLAMINO ALKYLOXY)-5-NITROPHENYL)-1,4-DIHYDROPYRIDINES AS ANTIHYPERTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-08-03 | — | — | WO | disclosed |