SCHEMBL6859005

SCHEMBL6859005

O=[N+]([O-])c1ccccc1OCC(O)CO

nearest known ligand 0.68

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.68
RAB9A P51151 3/20 0.60
NPC1 O15118 2/20 0.60
RECQL P46063 1/20 0.60
KMT2A Q03164 5/20 0.57
ALDH1A1 P00352 6/20 0.56
CYP1A2 P05177 3/20 0.55
KDM4E B2RXH2 3/20 0.55
LMNA P02545 2/20 0.55
AGTR1 P30556 1/20 0.55
MEN1 O00255 2/20 0.53
CYP2C19 P33261 1/20 0.53
HTT P42858 2/20 0.52
MAPT P10636 1/20 0.51
NPY1R P25929 1/20 0.51
NPY2R P49146 1/20 0.51
TDP1 Q9NUW8 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.48
POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29742389 1.00 L3MBTL1 (0.68) L3MBTL1RAB9ANPC1RECQLKMT2A
SCHEMBL7447113 0.92 L3MBTL1 (0.67) L3MBTL1RAB9ANPC1RECQLKMT2A
SCHEMBL7366723 0.86 L3MBTL1 (0.71) L3MBTL1RAB9ANPC1RECQLKMT2A
SCHEMBL11128346 0.85 CYP1A2 (0.54) L3MBTL1RAB9ANPC1RECQLKMT2A
SCHEMBL11128344 0.85 CYP1A2 (0.54) L3MBTL1RAB9ANPC1RECQLKMT2A
Nitric Acid SCHEMBL8753749 0.84 L3MBTL1 (0.51) L3MBTL1RAB9ANPC1RECQLKMT2A
Nitric Acid SCHEMBL8754463 0.84 L3MBTL1 (0.51) L3MBTL1RAB9ANPC1RECQLKMT2A
SCHEMBL27520599 0.84 L3MBTL1 (0.64) L3MBTL1RAB9ANPC1RECQLKMT2A
SCHEMBL10453566 0.83 L3MBTL1 (0.62) L3MBTL1RAB9ANPC1RECQLKMT2A
SCHEMBL2474599 0.83 L3MBTL1 (0.62) L3MBTL1RAB9ANPC1RECQLKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4061180-A1 DYEING OR LIGHTENING PROCESS USING A HAND-HELD STYLING DEVICE AND A SUBSTRATE L'OREAL (FR) 2022-09-28 EP disclosed
CN-113372568-B Preparation method of neodymium-based or holmium-based chiral metal-organic porous crystalline material, prepared material and application thereof 合肥工业大学 2022-07-22 CN disclosed
CN-113372568-A Preparation method of neodymium-based or holmium-based chiral metal-organic porous crystalline material, prepared material and application thereof 合肥工业大学 2021-09-10 CN disclosed
US-10696583-B2 Composition for strengthening glass C-BOND SYSTEMS, LLC (US) 2020-06-30 US disclosed
WO-2015097310-A1 LIGHTENING DYEING PROCESS USING A SUBSTRATE BEARING AT LEAST ONE OXIDIZING AGENT AND AN AQUEOUS COMPOSITION COMPRISING ONE OR MORE DIRECT DYES L'OREAL (FR) 2015-07-02 WO disclosed
WO-2015097308-A1 DYEING PROCESS USING AN INSOLUBLE SUBSTRATE BEARING AT LEAST ONE DIRECT DYE AND AN AQUEOUS COMPOSITION L'OREAL (FR) 2015-07-02 WO disclosed
US-20140141260-A1 COMPOSITION FOR STRENGTHENING GLASS ROK INVESTMENT GROUP LIMITED (UK) 2014-05-22 US disclosed
US-8541573-B2 Substituted sulfonamide compounds GRUENENTHAL GMBH (DE) 2013-09-24 US disclosed
US-8541573-B2 Substituted sulfonamide compounds GRUENENTHAL GMBH (DE) 2013-09-24 US disclosed
WO-2013009691-A1 COMPOSITION FOR STRENGTHENING GLASS ROK PROTECTIVE SYSTEMS, INC. (US) 2013-01-17 WO disclosed
US-20090253669-A1 Substituted Sulfonamide Compounds GRUENENTHAL GMBH (DE) 2009-10-08 US disclosed
WO-2009115257-A1 SUBSTITUTED SULFONAMIDE DERIVATIVES Grünenthal GmbH (DE) 2009-09-24 WO disclosed
WO-2009109364-A1 SUBSTITUTED SULFONAMIDE DERIVATIVES Grünenthal GmbH (DE) 2009-09-11 WO disclosed
EP-1456362-A2 METHOD FOR THE GENERATION OF PROTEINS WITH NEW ENZYMATIC FUNCTION California Institute of Technology (US) 2004-09-15 EP disclosed
WO-2003068907-A2 METHOD FOR THE GENERATION OF PROTEINS WITH NEW ENZYMATIC FUNCTION CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2003-08-21 WO disclosed
US-4209447-A FUNGICIDES, BACTERICIDES JANSSEN PHARMACEUTICA N.V. (BE) 1980-06-24 US disclosed
US-4154738-A 1-(2-AR-4-ARYLOXYMETHYL-1,3-DIOXOLAN-2-YL-METHYL)-IMIDAZOLES, FUNGICIDES, BACTERICIDES JANSSEN PHARMACEUTICA N.V. (BE) 1979-05-15 US disclosed
US-4141908-A FUNGICIDES, BACTERICIDES JANSSEN PHARMACEUTICA N.V. (BE) 1979-02-27 US disclosed
US-4139540-A FUNGICIDE, BACTERICIDE INTERMEDIATE JANSSEN PHARMACEUTICA N.V. (BE) 1979-02-13 US disclosed
US-4101665-A FUNGICIDES, BACTERICIDES JANSSEN PHARMACEUTICA N.V. (BE) 1978-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090253669-A1 Substituted Sulfonamide Compounds SULT2A1, STS, SULT1A1 L3MBTL1 4883/4885RAB9A 2485/4885NPC1 2399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.