Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440796 | 0.84 | CTSK (0.64) | CTSKCTSSCA1CA2 | |
| SCHEMBL14037661 | 0.79 | CA1 (0.51) | CTSKHDAC4HDAC1HDAC6CTSS | |
| SCHEMBL22338809 | 0.79 | CA1 (0.51) | CTSKHDAC4HDAC1HDAC6CTSS | |
| SCHEMBL7443743 | 0.79 | CTSK (0.51) | CTSKCTSSCA1CA2 | |
| SCHEMBL7433111 | 0.78 | CTSK (0.49) | CTSKCTSSCA1CA2 | |
| SCHEMBL7448540 | 0.78 | CTSS (0.42) | CTSKHDAC4HDAC1HDAC6CTSS | |
| SCHEMBL7436561 | 0.76 | CTSK (0.47) | CTSKCTSSCA1CA2 | |
| SCHEMBL7447154 | 0.73 | CA12 (0.34) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL7447134 | 0.73 | CA12 (0.34) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL7443442 | 0.73 | CTSK (0.43) | CTSKCTSSCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187905-B1 | PEPTIDE COMPOUND WHICH INHIBITS VIRAL PROTEINASES; VIRICIDES FOR HEPATITIS C, HEPATITIS G, AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2001-02-13 | — | — | US | disclosed |