Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.45 |
| ▸ | PPID | Q08752 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18065659 | 0.91 | MMP8 (0.53) | MMP8ALDH1A1TSHRSRRPPID | |
| SCHEMBL28240288 | 0.86 | MMP8 (0.49) | MMP8ALDH1A1TSHRSRRPPID | |
| SCHEMBL28767197 | 0.85 | MMP8 (0.48) | MMP8ALDH1A1TSHRSRRPPID | |
| Hydrochloric Acid SCHEMBL4841802 | 0.83 | ABCB1 (0.46) | ALDH1A1SRRMEN1KMT2ANPC1 | |
| SCHEMBL1646942 | 0.81 | EPHX1 (0.50) | MMP8ALDH1A1TSHRSRRPPID | |
| SCHEMBL1645938 | 0.81 | EPHX1 (0.50) | MMP8ALDH1A1TSHRSRRPPID | |
| SCHEMBL23750350 | 0.80 | ACE (0.47) | SLC15A1NPC1ALPIPKMPTGS1 | |
| SCHEMBL21610480 | 0.80 | ACE (0.47) | SLC15A1NPC1ALPIPKMPTGS1 | |
| SCHEMBL12268225 | 0.80 | TRPA1 (0.53) | MMP8ALDH1A1TSHRSRRPPID | |
| SCHEMBL12446348 | 0.80 | MMP8 (0.51) | MMP8ALDH1A1TSHRSRRPPID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998009987-A1 | LACTAM INHIBITORS OF THROMBIN | BIOCHEM PHARMA, INC. (CA) | 1998-03-12 | — | — | WO | disclosed |