Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TACR1 | P25103 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | ACAT2 | Q9BWD1 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324799 | 0.92 | NISCH (0.35) | SMN1; SMN2ALDH1A1CTSDSLC6A2SLC6A3 | |
| SCHEMBL7326003 | 0.77 | ALDH1A1 (0.35) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL7334912 | 0.76 | CYP19A1 (0.38) | CYP19A1CTSDSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL7334916 | 0.76 | CYP19A1 (0.38) | CYP19A1CTSDSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL11851101 | 0.73 | C3AR1 (0.45) | SMN1; SMN2ALDH1A1ACAT2 | |
| Hydrochloric Acid SCHEMBL11846468 | 0.71 | C3AR1 (0.44) | SMN1; SMN2ALDH1A1ACAT2 | |
| SCHEMBL7327606 | 0.70 | NPC1 (0.33) | SMN1; SMN2 | |
| SCHEMBL7328837 | 0.70 | NPC1 (0.33) | SMN1; SMN2 | |
| SCHEMBL7325274 | 0.70 | NPC1 (0.33) | SMN1; SMN2 | |
| SCHEMBL7327602 | 0.70 | NPC1 (0.33) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128337-A | Hypotensive agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-07-07 | — | — | US | disclosed |