SCHEMBL7447247

SCHEMBL7447247

c1[nH]nnc1C1CCNCC1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 1/20 0.42
SLC18A3 Q16572 1/20 0.38
SIGMAR1 Q99720 1/20 0.38
HRH3 Q9Y5N1 1/20 0.37
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
USP7 Q93009 1/20 0.35
HTR2C P28335 6/20 0.34
MKNK1 Q9BUB5 2/20 0.33
MKNK2 Q9HBH9 2/20 0.33
ADRB2 P07550 1/20 0.33
PLAT P00750 1/20 0.33
MAPT P10636 1/20 0.33
THRB P10828 1/20 0.33
HTR1A P08908 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9551450 0.88 HTR3A (0.39) HRH4HTR2C
SCHEMBL2820732 0.87
Hydrochloric Acid SCHEMBL9551444 0.86 HTR3A (0.38) HRH4HTR2C
SCHEMBL184035 0.83 HRH4 (0.36) HRH4HRH3KMT2A
SCHEMBL5603196 0.83
SCHEMBL5602384 0.81 HRH4 (0.35) HRH4HRH3KMT2A
SCHEMBL5602329 0.81 HRH4 (0.35) HRH4HRH3KMT2A
SCHEMBL4798376 0.81 HRH4 (0.35) HRH4HRH3KMT2A
SCHEMBL5601695 0.81 HRH4 (0.35) HRH4HRH3KMT2A
SCHEMBL5600191 0.81 HRH4 (0.35) HRH4HRH3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993019059-A1 ANTIVIRAL PEPTIDES PFIZER LIMITED (GB) 1993-09-30 WO disclosed