Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | ELANE | P08246 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7842064 | 0.81 | CTRB1 (0.45) | RAB9AKMT2AELANEALDH1A1CTSS | |
| SCHEMBL6506533 | 0.81 | KMT2A (0.40) | RAB9AKMT2AELANEALDH1A1HPGD | |
| SCHEMBL6507279 | 0.74 | ELANE (0.39) | KMT2AELANEMEN1ALDH1A1HPGD | |
| SCHEMBL6640437 | 0.74 | CTRB1 (0.55) | KMT2AELANEMEN1ALDH1A1HPGD | |
| SCHEMBL7439886 | 0.71 | ELANE (0.38) | KMT2AELANE | |
| SCHEMBL7448303 | 0.68 | ELANE (0.38) | RAB9AKMT2AELANEHPGDCYP2D6 | |
| SCHEMBL6803473 | 0.67 | ELANE (0.36) | ELANE | |
| SCHEMBL6498024 | 0.67 | ELANE (0.37) | RAB9AKMT2AELANECYP2D6NPC1 | |
| SCHEMBL6532128 | 0.64 | ELANE (0.47) | ELANE | |
| SCHEMBL6498805 | 0.64 | ELANE (0.46) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996037485-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1996-11-28 | — | — | WO | claimed |