Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6498024 | 0.89 | ELANE (0.37) | ELANENPC1RAB9AF2KMT2A | |
| SCHEMBL8619050 | 0.81 | ELANE (0.38) | ELANENPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL27531939 | 0.79 | ELANE (0.57) | ELANE | |
| SCHEMBL6809994 | 0.78 | CTRB1 (0.38) | ELANENPC1RAB9AHPGDKMT2A | |
| SCHEMBL7831962 | 0.77 | CTRB1 (0.42) | ELANENPC1RAB9AHPGDKMT2A | |
| SCHEMBL6803473 | 0.77 | ELANE (0.36) | ELANE | |
| SCHEMBL27364609 | 0.72 | ELANE (0.58) | ELANE | |
| SCHEMBL7842073 | 0.72 | CTRB1 (0.47) | ELANENPC1RAB9AKMT2A | |
| SCHEMBL6799137 | 0.72 | CTRB1 (0.39) | ELANENPC1RAB9AF2KMT2A | |
| SCHEMBL7840950 | 0.71 | CTRB1 (0.43) | ELANENPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996037485-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1996-11-28 | — | — | WO | disclosed |