Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 10/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.49 |
| ▸ | CTSK | P43235 | 3/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444283 | 0.93 | ELANE (0.51) | ELANECTRB1CTSKCTSSCTSL | |
| SCHEMBL6506622 | 0.91 | ELANE (0.46) | ELANECTRB1TACR1 | |
| SCHEMBL6497427 | 0.88 | ELANE (0.47) | ELANECTRB1KMT2AMEN1TACR1 | |
| SCHEMBL7447429 | 0.88 | ELANE (0.47) | ELANECTRB1KMT2AMEN1TACR1 | |
| SCHEMBL7829580 | 0.87 | ELANE (0.43) | ELANECTRB1KMT2A | |
| SCHEMBL6806792 | 0.84 | ELANE (0.43) | ELANECTRB1 | |
| SCHEMBL6803263 | 0.83 | ELANE (0.45) | ELANECTRB1TACR1 | |
| SCHEMBL6496064 | 0.83 | ELANE (0.47) | ELANECTRB1TACR1 | |
| SCHEMBL7449581 | 0.83 | ELANE (0.46) | ELANECTRB1KMT2AMEN1 | |
| SCHEMBL7444621 | 0.82 | ELANE (0.45) | ELANECTRB1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828721-B1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | SEARLE & CO (US) | 2001-11-14 | — | — | EP | claimed |