Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6500847 | 0.92 | ELANE (0.45) | ELANECTRB1LMNATP53KLKB1 | |
| SCHEMBL6497427 | 0.92 | ELANE (0.47) | ELANECTRB1PTPN1PTPN2ALDH1A1 | |
| SCHEMBL7447429 | 0.92 | ELANE (0.47) | ELANECTRB1PTPN1PTPN2ALDH1A1 | |
| SCHEMBL6802037 | 0.88 | ELANE (0.46) | ELANECTRB1ALDH1A1LMNAHTT | |
| SCHEMBL6803240 | 0.88 | ELANE (0.43) | ELANECTRB1LMNAUSP2 | |
| SCHEMBL6505687 | 0.87 | ELANE (0.49) | ELANECTRB1PTPN1KMT2A | |
| SCHEMBL7444283 | 0.87 | ELANE (0.51) | ELANECTRB1MEN1KMT2A | |
| SCHEMBL7841675 | 0.86 | ELANE (0.48) | ELANECTRB1 | |
| SCHEMBL6805848 | 0.86 | ELANE (0.44) | ELANECTRB1LMNA | |
| SCHEMBL7844661 | 0.85 | CTRB1 (0.49) | ELANECTRB1PTPN1PTPN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996037485-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1996-11-28 | — | — | WO | disclosed |