Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7447489 | 1.00 | HTR3A (0.56) | HTR3A | |
| Hydrochloric Acid SCHEMBL7438540 | 0.99 | HTR3A (0.55) | HTR3A | |
| Hydrochloric Acid SCHEMBL7438552 | 0.99 | HTR3A (0.55) | HTR3A | |
| SCHEMBL7438929 | 0.86 | TAS1R3 (0.59) | — | |
| SCHEMBL7438921 | 0.86 | TAS1R3 (0.59) | — | |
| Hydrochloric Acid SCHEMBL7432770 | 0.85 | TAS1R3 (0.57) | — | |
| Hydrochloric Acid SCHEMBL7432766 | 0.85 | TAS1R3 (0.57) | — | |
| SCHEMBL7448582 | 0.84 | HTR3A (0.55) | HTR3A | |
| SCHEMBL7437543 | 0.84 | TAS1R3 (0.60) | HTR3A | |
| SCHEMBL7437549 | 0.84 | TAS1R3 (0.60) | HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491148-A | TREATING GASTROINTESTINAL, CARDIOVASCULAR, CENTRAL NERVOUS SYSTEM DISORDERS, EMESIS, PAIN | SYNTEX (U.S.A.) INC. (US) | 1996-02-13 | — | — | US | disclosed |