Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 11/20 | 0.39 |
| ▸ | F10 | P00742 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 2/20 | 0.36 |
| ▸ | MC3R | P41968 | 2/20 | 0.36 |
| ▸ | MC1R | Q01726 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7486565 | 0.92 | F2 (0.38) | PLAUF2F10PRSS1F7 | |
| SCHEMBL7488328 | 0.91 | DPP4 (0.38) | F2F10NPC1F7 | |
| SCHEMBL7493490 | 0.91 | NOS3 (0.39) | F2F10MEN1NPC1RAB9A | |
| SCHEMBL7485981 | 0.90 | PLAU (0.41) | PLAUF2F10MEN1NPC1 | |
| SCHEMBL7488683 | 0.90 | F2 (0.37) | F2F10MEN1NPC1RAB9A | |
| SCHEMBL7491657 | 0.89 | MEN1 (0.40) | F2F10MEN1KMT2A | |
| SCHEMBL7491327 | 0.88 | F10 (0.38) | PLAUF2F10PRSS1F7 | |
| SCHEMBL7447646 | 0.87 | F2 (0.39) | PLAUF2F10NPC1PRSS1 | |
| SCHEMBL7491570 | 0.87 | F10 (0.42) | F2F10NPC1PRSS1F7 | |
| SCHEMBL7448832 | 0.86 | F2 (0.39) | PLAUF2F10NPC1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-B1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RES LAB (KR) | 2002-01-09 | — | — | EP | disclosed |
| US-6201006-B1 | ANTICOAGULANTS | C & C RESEARCH LABORATORIES (KR) | 2001-03-13 | — | — | US | disclosed |
| EP-0918768-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C Research Laboratories (KR) | 1999-06-02 | — | — | EP | disclosed |
| WO-1997045424-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RESEARCH LABORATORIES (KR) | 1997-12-04 | — | — | WO | disclosed |