Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.38 |
| ▸ | F2 | P00734 | 4/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | CPT1A | P50416 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7486565 | 0.88 | F2 (0.38) | F10F2F7PRSS1PLAU | |
| SCHEMBL7447663 | 0.88 | PLAU (0.40) | F10F2F7PRSS1PLAU | |
| SCHEMBL7488328 | 0.87 | DPP4 (0.38) | F10F2F7 | |
| SCHEMBL7491657 | 0.85 | MEN1 (0.40) | F10F2 | |
| SCHEMBL7447646 | 0.80 | F2 (0.39) | F10F2ITGB3ITGA2BSPHK2 | |
| SCHEMBL7491570 | 0.80 | F10 (0.42) | F10F2SPHK2F7PRSS1 | |
| SCHEMBL7488683 | 0.80 | F2 (0.37) | F10F2ITGB3ITGA2BSPHK2 | |
| SCHEMBL7448832 | 0.80 | F2 (0.39) | F10F2ITGB3ITGA2BSPHK2 | |
| SCHEMBL7493490 | 0.79 | NOS3 (0.39) | F10F2PRSS1SPHK1 | |
| SCHEMBL7488281 | 0.78 | F2 (0.38) | F10F2SPHK2F7PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-B1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RES LAB (KR) | 2002-01-09 | — | — | EP | disclosed |
| US-6201006-B1 | ANTICOAGULANTS | C & C RESEARCH LABORATORIES (KR) | 2001-03-13 | — | — | US | disclosed |