Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 19/20 | 0.50 |
| ▸ | MMP9 | P14780 | 17/20 | 0.50 |
| ▸ | MMP1 | P03956 | 13/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7447702 | 0.86 | MMP2 (0.64) | MMP2MMP9MMP1MMP3 | |
| SCHEMBL7678510 | 0.82 | MMP2 (0.63) | MMP2MMP9MMP1MMP3 | |
| SCHEMBL7450290 | 0.82 | MMP2 (0.58) | MMP2MMP9MMP1MMP3 | |
| SCHEMBL7673477 | 0.79 | MMP2 (0.43) | MMP2MMP9MMP1 | |
| SCHEMBL7449006 | 0.79 | MMP2 (0.74) | MMP2MMP9MMP1 | |
| SCHEMBL7502559 | 0.76 | MMP2 (0.66) | MMP2MMP9MMP1MMP3 | |
| SCHEMBL7506026 | 0.72 | MMP2 (0.83) | MMP2MMP9MMP1MMP3 | |
| SCHEMBL7454086 | 0.72 | MMP2 (0.74) | MMP2MMP9MMP1 | |
| SCHEMBL7450286 | 0.70 | MMP2 (0.78) | MMP2MMP9MMP1MMP3 | |
| SCHEMBL7507356 | 0.70 | MMP2 (0.78) | MMP2MMP9MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001930-A2 | N-HYDROXYFORMAMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | Abbott Laboratories (US) | 2000-05-24 | — | — | EP | claimed |
| WO-1999006361-A2 | N-HYDROXYFORMAMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 1999-02-11 | — | — | WO | claimed |
| EP-1001930-A2 | N-HYDROXYFORMAMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | Abbott Laboratories (US) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999006361-A2 | N-HYDROXYFORMAMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 1999-02-11 | — | — | WO | disclosed |