Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 19/20 | 0.58 |
| ▸ | MMP1 | P03956 | 10/20 | 0.58 |
| ▸ | MMP9 | P14780 | 10/20 | 0.58 |
| ▸ | MMP3 | P08254 | 8/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7450286 | 0.87 | MMP2 (0.78) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7447708 | 0.82 | MMP2 (0.50) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7515464 | 0.78 | MMP2 (0.75) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7454086 | 0.77 | MMP2 (0.74) | MMP2MMP1MMP9 | |
| SCHEMBL7449006 | 0.75 | MMP2 (0.74) | MMP2MMP1MMP9 | |
| SCHEMBL7507356 | 0.74 | MMP2 (0.78) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7502929 | 0.73 | MMP2 (1.00) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7677270 | 0.72 | MMP2 (1.00) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7447702 | 0.71 | MMP2 (0.64) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7555583 | 0.71 | MMP2 (0.73) | MMP2MMP1MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001930-A2 | N-HYDROXYFORMAMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | Abbott Laboratories (US) | 2000-05-24 | — | — | EP | claimed |
| WO-1999006361-A2 | N-HYDROXYFORMAMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 1999-02-11 | — | — | WO | claimed |