Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 13/20 | 0.68 |
| ▸ | MMP2 | P08253 | 16/20 | 0.54 |
| ▸ | MMP1 | P03956 | 3/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7450099 | 1.00 | MMP3 (0.68) | MMP3MMP2MMP1EGFRPOLB | |
| SCHEMBL7498355 | 0.81 | MMP3 (1.00) | MMP3MMP2MMP1ALDH1A1HPGD | |
| SCHEMBL7507012 | 0.78 | MMP3 (0.71) | MMP3MMP2MMP1ALDH1A1HPGD | |
| SCHEMBL7504451 | 0.78 | MMP3 (0.77) | MMP3MMP2MMP1ALDH1A1HPGD | |
| SCHEMBL7504389 | 0.78 | MMP2 (0.76) | MMP3MMP2MMP1ALDH1A1HPGD | |
| SCHEMBL7509014 | 0.74 | MMP2 (0.73) | MMP3MMP2MMP1ALDH1A1HPGD | |
| SCHEMBL7499759 | 0.72 | MMP2 (0.67) | MMP3MMP2MMP1ALDH1A1HPGD | |
| SCHEMBL7453489 | 0.71 | MMP2 (1.00) | MMP3MMP2MMP1ALDH1A1HPGD | |
| SCHEMBL7501260 | 0.70 | MMP2 (0.64) | MMP3MMP2MMP1ALDH1A1HPGD | |
| SCHEMBL7497786 | 0.70 | MMP2 (1.00) | MMP3MMP2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001930-A2 | N-HYDROXYFORMAMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | Abbott Laboratories (US) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999006361-A2 | N-HYDROXYFORMAMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 1999-02-11 | — | — | WO | disclosed |