Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 19/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 14/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 12/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 12/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449025 | 0.90 | ADRA1B (0.41) | F2PRSS1PRSS2PRSS3ADRA1B | |
| Trifluoroacetic Acid SCHEMBL8067875 | 0.86 | ADRA1B (0.39) | F2PRSS1PRSS2PRSS3ADRA1B | |
| SCHEMBL8069721 | 0.82 | F2 (0.48) | F2PRSS1PRSS2PRSS3ADRA1B | |
| SCHEMBL7333722 | 0.81 | F2 (0.60) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7334782 | 0.77 | F2 (0.49) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7225450 | 0.77 | F2 (0.54) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7233636 | 0.76 | F2 (0.53) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7224399 | 0.75 | F2 (0.43) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7227459 | 0.75 | F2 (0.43) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7224396 | 0.75 | F2 (0.44) | F2PRSS1PRSS2PRSS3F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204384-B1 | THROMBIN INHIBITOR; ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. | 2001-03-20 | — | — | US | disclosed |
| US-6011047-A | Substituted 3-amino-2-hydroxyphenylacetamide derivatives as enzyme inhibitors | CORVAS INTERNATIONAL INC. (US) | 2000-01-04 | — | — | US | disclosed |
| WO-1999026920-A1 | SUBSTITUTED 3-AMINO-2-HYDROXYPHENYLACETAMIDE DERIVATIVES AS ENZYME INHIBITORS (II) | CORVAS INTERNATIONAL, INC. (US) | 1999-06-03 | — | — | WO | disclosed |