Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 18/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 15/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 14/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 14/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448006 | 0.82 | F2 (0.45) | F2PRSS1PRSS2PRSS3ADRA1B | |
| SCHEMBL7449025 | 0.72 | ADRA1B (0.41) | F2PRSS1PRSS2PRSS3ADRA1B | |
| Trifluoroacetic Acid SCHEMBL8067875 | 0.69 | ADRA1B (0.39) | F2PRSS1PRSS2PRSS3ADRA1B | |
| SCHEMBL6762058 | 0.65 | F2 (0.54) | F2PRSS1PRSS2PRSS3ADRA1B | |
| SCHEMBL7333722 | 0.64 | F2 (0.60) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL14563534 | 0.63 | ALDH1A1 (0.46) | F2PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL6162125 | 0.61 | F2 (0.51) | F2PRSS1PRSS2PRSS3ADRA1B | |
| SCHEMBL8553223 | 0.61 | PRSS1 (0.63) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL16485210 | 0.61 | CTSC (0.57) | — | |
| SCHEMBL31615866 | 0.61 | HPGD (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6011047-A | Substituted 3-amino-2-hydroxyphenylacetamide derivatives as enzyme inhibitors | CORVAS INTERNATIONAL INC. (US) | 2000-01-04 | — | — | US | disclosed |