Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11135874 | 0.89 | SMN1; SMN2 (0.55) | FFAR1FFAR4KEAP1HDAC3MAPK1 | |
| SCHEMBL11142207 | 0.87 | SMN1; SMN2 (0.53) | FFAR1FFAR4KEAP1HDAC3MAPK1 | |
| SCHEMBL7916098 | 0.85 | ALDH1A1 (0.55) | FFAR1FFAR4KEAP1HDAC3MAPK1 | |
| SCHEMBL15065969 | 0.83 | FFAR1 (0.45) | FFAR1FFAR4MAPT | |
| SCHEMBL8335434 | 0.83 | FFAR1 (0.45) | FFAR1FFAR4KEAP1HDAC3MAPK1 | |
| SCHEMBL11137418 | 0.79 | FFAR1 (0.54) | FFAR1FFAR4HDAC3MAPK1ADRA1A | |
| SCHEMBL561059 | 0.78 | FFAR1 (0.62) | FFAR1FFAR4CYP2C19 | |
| SCHEMBL16050096 | 0.78 | AKR1B1 (0.71) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL3888886 | 0.78 | CALM1 (0.50) | FFAR1FFAR4SMN1; SMN2CYP2C19 | |
| SCHEMBL6722156 | 0.77 | TDP1 (0.46) | FFAR1FFAR4MAPTAKR1B1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165501-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000051975-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |