Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.75 |
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18926546 | 0.86 | LMNA (1.00) | LMNAHRH3MAPK1RAB9AMEN1 | |
| SCHEMBL996088 | 0.84 | LMNA (0.53) | LMNAHRH3MAPK1RAB9AALDH1A1 | |
| SCHEMBL22422293 | 0.84 | LMNA (0.96) | LMNAHRH3ALDH1A1 | |
| SCHEMBL14485306 | 0.81 | LMNA (0.81) | LMNAHRH3MAPK1RAB9AMEN1 | |
| SCHEMBL5730065 | 0.79 | LMNA (0.78) | LMNAHRH3MAPK1RAB9AMEN1 | |
| SCHEMBL6292266 | 0.78 | LMNA (0.59) | LMNAHRH3MAPK1RAB9AMEN1 | |
| SCHEMBL12203973 | 0.78 | LMNA (0.81) | LMNAHRH3MEN1ALDH1A1KMT2A | |
| SCHEMBL4501961 | 0.78 | LMNA (0.81) | LMNAHRH3MAPK1RAB9AMEN1 | |
| SCHEMBL4517684 | 0.78 | LMNA (0.81) | LMNAHRH3MAPK1RAB9AMEN1 | |
| SCHEMBL3453099 | 0.76 | LMNA (0.79) | LMNAHRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863755-A4 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 1999-01-20 | — | — | EP | disclosed |
| EP-0863755-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997025033-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |