Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.63 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | NOS2 | P35228 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | NOS3 | P29474 | 2/20 | 0.47 |
| ▸ | NOS1 | P29475 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8086204 | 1.00 | TAS1R3 (0.63) | TAS1R3TAS1R1SMN1; SMN2NOS2HPGD | |
| SCHEMBL7448092 | 1.00 | TAS1R3 (0.63) | TAS1R3TAS1R1SMN1; SMN2NOS2HPGD | |
| SCHEMBL28965883 | 1.00 | TAS1R3 (0.63) | TAS1R3TAS1R1SMN1; SMN2NOS2HPGD | |
| SCHEMBL10777518 | 0.82 | NOS2 (0.66) | NOS2PPARG | |
| SCHEMBL10777506 | 0.82 | NOS2 (0.66) | NOS2PPARG | |
| SCHEMBL10777498 | 0.82 | NOS2 (0.66) | NOS2PPARG | |
| SCHEMBL10652157 | 0.81 | NOS2 (0.78) | NOS2ALDH1A1PPARGMAPTNOS3 | |
| SCHEMBL12761015 | 0.81 | NOS2 (0.78) | NOS2ALDH1A1PPARGMAPTNOS3 | |
| SCHEMBL10725102 | 0.81 | NOS2 (0.78) | NOS2ALDH1A1PPARGMAPTNOS3 | |
| SCHEMBL10725101 | 0.81 | NOS2 (0.78) | NOS2ALDH1A1PPARGMAPTNOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0817795-B1 | NOVEL 4-SUBSTITUTED-3-PEPTIDYL-AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE INHIBITOR | NAEJA PHARMACEUTICAL INC (CA) | 2000-11-15 | — | — | EP | claimed |
| US-5986108-A | ENZYME INHIBITORS | SYNPHAR LABORATORIES, INC. (CA) | 1999-11-16 | — | — | US | claimed |
| EP-0817795-A1 | NOVEL 4-SUBSTITUTED-3-PEPTIDYL-AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE INHIBITOR | SYNPHAR LABORATORIES INC. (CA) | 1998-01-14 | — | — | EP | claimed |
| WO-1996032408-A1 | NOVEL 4-SUBSTITUTED-3-PEPTIDYL-AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE INHIBITOR | SYNPHAR LABORATORIES, INC. (US) | 1996-10-17 | — | — | WO | claimed |
| CN-114645037-A | Means and methods for detoxification of ochratoxin A | 艾尔柏股份公司 | 2022-06-21 | — | — | CN | disclosed |