SCHEMBL7448157

SCHEMBL7448157

Ic1ccc(N2c3ccccc3-c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 3/20 0.43
FAAH O00519 1/20 0.43
ALDH1A1 P00352 2/20 0.42
CES2 O00748 1/20 0.42
BCHE P06276 1/20 0.42
GAA P10253 1/20 0.42
CES1 P23141 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
GNG2 P59768 1/20 0.36
GNB1 P62873 1/20 0.36
PDE6D O43924 1/20 0.34
SCN2A Q99250 3/20 0.32
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
DNMT1 P26358 1/20 0.32
RAD52 P43351 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10013271 0.89 ALDH1A1 (0.50) MGLLALDH1A1CES2BCHEGAA
SCHEMBL64530 0.82 PDE6D (0.47) MGLLFAAHALDH1A1CES2BCHE
SCHEMBL19602228 0.81 ALDH1A1 (0.59) MGLLALDH1A1CES2BCHEGAA
SCHEMBL12320704 0.81 ALDH1A1 (0.59) MGLLALDH1A1CES2BCHEGAA
SCHEMBL17929852 0.79 ALDH1A1 (0.57) MGLLALDH1A1CES2BCHEGAA
SCHEMBL14830555 0.79 CES1 (0.73) MGLLFAAHALDH1A1CES2BCHE
SCHEMBL13053126 0.78 NPSR1 (0.42) MGLLALDH1A1CES2BCHEGAA
SCHEMBL12334414 0.78 PDE6D (0.53) MGLLFAAHALDH1A1CES2BCHE
SCHEMBL20624618 0.78 ALDH1A1 (0.42) MGLLALDH1A1CES2BCHEGAA
SCHEMBL6364561 0.78 MGLL (0.43) MGLLFAAHALDH1A1CES2BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6436558-B1 SUBSTRATE HAVING PROVIDED THEREON AN ANODE FOR INJECTING HOLES, A CATHODE FOR INJECTING ELECTRONS, AND AT LEAST ONE ORGANIC COMPOUND LAYER THEREBETWEEN, WHEREIN THE ORGANIC COMPOUND LAYER CONTAINS AT LEAST ONE COMPOUND REPRESENTED BY FUJI PHOTO FILM CO., LTD. 2002-08-20 US disclosed