Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438831 | 0.85 | BRD4 (0.45) | TSHRATMKMT2ANPC1RAB9A | |
| SCHEMBL7410161 | 0.79 | CA12 (0.51) | TSHRATMKMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL182586 | 0.77 | ALDH1A1 (0.40) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7445551 | 0.76 | GAA (0.39) | KMT2AMEN1GAAHPGDLMNA | |
| SCHEMBL7354826 | 0.76 | CA12 (0.35) | TSHRKMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL14507082 | 0.74 | NR1I2 (0.51) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 | |
| SCHEMBL6749782 | 0.73 | KDM4E (0.61) | TSHRATMKMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL3664285 | 0.71 | ALDH1A1 (0.33) | ALDH1A1C5AR1 | |
| SCHEMBL6749657 | 0.71 | PGR (0.57) | TSHRKMT2ASMN1; SMN2MAPK1MEN1 | |
| SCHEMBL8749765 | 0.71 | SMN1; SMN2 (0.36) | TSHRKMT2ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946528-A2 | OXYGEN OR SULFUR CONTAINING 5-MEMBERED HETEROAROMATICS AS FACTOR Xa INHIBITORS | Du Pont Pharmaceuticals Company (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998028282-A2 | OXYGEN OR SULFUR CONTAINING 5-MEMBERED HETEROAROMATICS AS FACTOR Xa INHIBITORS | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-07-02 | — | — | WO | disclosed |