Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | PDE5A | O76074 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 2/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7502173 | 0.93 | PDE5A (0.48) | LMNAPDE5AHPGD | |
| SCHEMBL7451626 | 0.87 | ALDH1A1 (0.46) | LMNAHPGDEPHX2 | |
| SCHEMBL6943689 | 0.83 | LMNA (0.45) | LMNAPDE5AHPGDAKR1B1APEX1 | |
| SCHEMBL6943685 | 0.83 | LMNA (0.45) | LMNAPDE5AHPGDAKR1B1APEX1 | |
| SCHEMBL7505574 | 0.82 | LMNA (0.43) | LMNAPDE5AHPGDAKR1B1APEX1 | |
| SCHEMBL7505566 | 0.82 | LMNA (0.43) | LMNAPDE5AHPGDAKR1B1APEX1 | |
| SCHEMBL6941529 | 0.81 | LMNA (0.50) | LMNAPDE5AHPGDAKR1B1APEX1 | |
| SCHEMBL7370696 | 0.80 | LMNA (0.45) | LMNAPDE5AHPGDAKR1B1APEX1 | |
| SCHEMBL7404538 | 0.79 | PDE5A (0.51) | LMNAPDE5AWDR5 | |
| SCHEMBL7404535 | 0.79 | PDE5A (0.51) | LMNAPDE5AWDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001030745-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-03 | — | — | WO | disclosed |