Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetradecylamine SCHEMBL28206008 | 0.82 | DNM1 (0.48) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL2269826 | 0.79 | — | — | |
| SCHEMBL27859966 | 0.78 | NR5A1 (0.44) | ALDH1A1TSHRTLR8 | |
| SCHEMBL9683872 | 0.78 | NR5A1 (0.44) | ALDH1A1TSHRTLR8 | |
| SCHEMBL9851145 | 0.78 | NR5A1 (0.44) | ALDH1A1TSHRTLR8 | |
| SCHEMBL4541652 | 0.76 | LTA4H (0.44) | TSHRTLR8 | |
| SCHEMBL7453122 | 0.76 | DNM1 (0.50) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Dodecylamine SCHEMBL11639644 | 0.74 | LTA4H (0.55) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL4268840 | 0.73 | CYP2D6 (0.48) | MAPT | |
| Decylamine SCHEMBL28794198 | 0.72 | DNM1 (0.81) | DNM1MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977743-A1 | PROTEASE INHIBITORS | Smithkline Beecham (US) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998049152-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-11-05 | — | — | WO | disclosed |