Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 19/20 | 0.44 |
| ▸ | F2R | P25116 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7437953 | 0.94 | ITGB3 (0.45) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| SCHEMBL7440757 | 0.94 | ITGB3 (0.45) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| SCHEMBL7452040 | 0.90 | ALDH1A1 (0.39) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| SCHEMBL7446583 | 0.84 | KMT2A (0.40) | ITGB3ITGA2BMEN1ALDH1A1MAPT | |
| SCHEMBL7441386 | 0.84 | ITGB3 (0.44) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| SCHEMBL7439730 | 0.84 | ALDH1A1 (0.39) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| SCHEMBL7444290 | 0.84 | ALDH1A1 (0.39) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| SCHEMBL7440109 | 0.84 | ALDH1A1 (0.39) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| SCHEMBL7448410 | 0.82 | KMT2A (0.46) | ITGB3ITGA2BF2RMEN1ALDH1A1 | |
| SCHEMBL7451021 | 0.82 | ITGB3 (0.49) | ITGB3ITGA2BF2RMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384028-B1 | TREATMENT OF CARDIOVASCULAR DISORDERS, ANTICOAGULANTS AND VALVE REPLACEMENT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |
| WO-1996029309-A1 | N-ACYLPIPERIDINYLCARBONYLAMINOCARBOXYLIC ACIDS AND THEIR USE AS GLYCOPROTEIN IIB/IIa ANTAGONISTS AND FIBRINOGEN-BLOOD PLATELETS BINDING INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-09-26 | — | — | WO | disclosed |