Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | MIF | P14174 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6720181 | 0.91 | MEN1 (0.85) | MEN1KMT2APKMMAPTAPEX1 | |
| SCHEMBL7450127 | 0.90 | MEN1 (0.80) | MEN1KMT2APKMMAPTAPEX1 | |
| SCHEMBL7450408 | 0.89 | MEN1 (0.62) | MEN1KMT2ALMNAPTBP1ALDH1A1 | |
| SCHEMBL14420811 | 0.88 | KMT2A (0.64) | MEN1KMT2APKMSUCNR1MIF | |
| SCHEMBL14075283 | 0.87 | MAPT (0.77) | MEN1KMT2APKMMAPTAPEX1 | |
| SCHEMBL7452855 | 0.86 | MEN1 (0.64) | MEN1KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL7450864 | 0.84 | MEN1 (0.67) | MEN1KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL13870858 | 0.83 | MEN1 (0.82) | MEN1KMT2ALMNAALDH1A1PKM | |
| SCHEMBL4098366 | 0.83 | MEN1 (0.67) | MEN1KMT2A | |
| SCHEMBL7450555 | 0.83 | MEN1 (1.00) | MEN1KMT2ALMNAALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001098274-A2 | SULPHONAMIDE DERIVATIVES | CELLTECH CHIROSCIENCE LIMITED (GB) | 2001-12-27 | — | — | WO | claimed |
| WO-2001098274-A2 | SULPHONAMIDE DERIVATIVES | CELLTECH CHIROSCIENCE LIMITED (GB) | 2001-12-27 | — | — | WO | disclosed |