Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | CASP3 | P42574 | 1/20 | 0.63 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.63 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.63 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.53 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7452610 | 0.90 | CASP3 (0.56) | MEN1KMT2ACASP3SENP8SENP7 | |
| SCHEMBL7452855 | 0.90 | MEN1 (0.64) | MEN1KMT2ACASP3SENP8SENP7 | |
| SCHEMBL7449361 | 0.90 | MEN1 (0.72) | MEN1KMT2ACASP3SENP8SENP7 | |
| SCHEMBL13870867 | 0.89 | CASP3 (0.74) | MEN1KMT2ACASP3SENP8SENP7 | |
| SCHEMBL7449687 | 0.88 | MEN1 (0.64) | MEN1KMT2ACASP3SENP8SENP7 | |
| SCHEMBL7453890 | 0.86 | MEN1 (0.70) | MEN1KMT2ACASP3SENP8SENP7 | |
| SCHEMBL7453014 | 0.85 | MEN1 (0.63) | MEN1KMT2ACASP3SENP8SENP7 | |
| SCHEMBL7450127 | 0.85 | MEN1 (0.80) | MEN1KMT2AAPEX1SUCNR1PKM | |
| SCHEMBL7372057 | 0.85 | KDM4E (0.64) | MEN1KMT2ACASP3SENP8SENP7 | |
| SCHEMBL7448446 | 0.84 | MEN1 (0.72) | MEN1KMT2ACASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001098274-A2 | SULPHONAMIDE DERIVATIVES | CELLTECH CHIROSCIENCE LIMITED (GB) | 2001-12-27 | — | — | WO | claimed |
| WO-2001098274-A2 | SULPHONAMIDE DERIVATIVES | CELLTECH CHIROSCIENCE LIMITED (GB) | 2001-12-27 | — | — | WO | disclosed |