Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALPL | P05186 | 1/20 | 0.52 |
| ▸ | ALPI | P09923 | 1/20 | 0.52 |
| ▸ | ALPG | P10696 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449268 | 0.91 | MEN1 (0.68) | MEN1KMT2ALMNANPSR1HPGD | |
| SCHEMBL7448446 | 0.89 | MEN1 (0.72) | MEN1KMT2ALMNAPTBP1PKM | |
| SCHEMBL7457708 | 0.87 | MEN1 (0.56) | MEN1KMT2ALMNAPKMGAA | |
| SCHEMBL7452610 | 0.86 | CASP3 (0.56) | MEN1KMT2ALMNAPTBP1PKM | |
| SCHEMBL7454553 | 0.84 | MEN1 (0.79) | MEN1KMT2ALMNAPKMALOX12 | |
| SCHEMBL8241750 | 0.83 | TCF4 (0.64) | MEN1KMT2ALMNAPTBP1PKM | |
| SCHEMBL26808973 | 0.83 | TCF4 (0.69) | MEN1KMT2ALMNAHPGDMAPK10 | |
| SCHEMBL7450548 | 0.83 | POLB (0.59) | MEN1KMT2ALMNANPSR1GAA | |
| SCHEMBL7452179 | 0.82 | MEN1 (0.56) | MEN1KMT2ALMNANPSR1HPGD | |
| SCHEMBL7445907 | 0.82 | MEN1 (0.65) | MEN1KMT2AGAAHPGDMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001098274-A2 | SULPHONAMIDE DERIVATIVES | CELLTECH CHIROSCIENCE LIMITED (GB) | 2001-12-27 | — | — | WO | disclosed |