Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449901 | 0.86 | ATM (0.36) | ATMALDH1A1PKMRAB9ANPC1 | |
| SCHEMBL7452233 | 0.86 | RAB9A (0.33) | ALDH1A1PKMRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7452035 | 0.85 | SLC6A2 (0.40) | ALDH1A1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL7451211 | 0.84 | SMN1; SMN2 (0.45) | ATMALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7837953 | 0.84 | SMN1; SMN2 (0.45) | ATMALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7837015 | 0.83 | ADA (0.47) | LMNAMAPTKMT2A | |
| SCHEMBL7452394 | 0.82 | CNR1 (0.31) | SMN1; SMN2KMT2AHPGDCNR1 | |
| SCHEMBL7454436 | 0.82 | MEN1 (0.34) | SMN1; SMN2KMT2AHPGDMAPK1CCR1 | |
| SCHEMBL7453035 | 0.82 | NPC1 (0.32) | ALDH1A1RAB9ANPC1KMT2ACNR1 | |
| SCHEMBL7449449 | 0.81 | ADA (0.47) | ALDH1A1PKMLMNASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001026605-A2 | IMMUNOSUPPRESSIVE COMPOSITION CONTAINING IL-2 INHIBITOR AND AN ADENOSINE DEAMINASE INHIBITOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-19 | — | — | WO | disclosed |