Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448681 | 0.90 | KMT2A (0.40) | ATMKMT2AMEN1MMP9MMP8 | |
| SCHEMBL7452291 | 0.88 | MEN1 (0.37) | ATMKMT2AMEN1ALDH1A1MMP9 | |
| SCHEMBL7448880 | 0.87 | PTGER1 (0.37) | ATMMMP9MMP8PTGER1ACACB | |
| SCHEMBL7827665 | 0.86 | APLNR (0.37) | KMT2AMEN1TDP1 | |
| SCHEMBL7448644 | 0.86 | ATM (0.35) | ATMKMT2AALDH1A1PKMCNR1 | |
| SCHEMBL7449545 | 0.86 | KMT2A (0.40) | KMT2AALDH1A1HPGD | |
| SCHEMBL7457342 | 0.86 | KMT2A (0.40) | KMT2AALDH1A1HPGD | |
| SCHEMBL7450779 | 0.85 | CTSG (0.37) | ATMMMP9MMP8PTGER1ACACB | |
| SCHEMBL7453353 | 0.84 | CNR1 (0.38) | ATMKMT2AMEN1MMP9MMP8 | |
| SCHEMBL7449714 | 0.84 | MMP9 (0.38) | ATMMMP9MMP8PTGER1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001026605-A2 | IMMUNOSUPPRESSIVE COMPOSITION CONTAINING IL-2 INHIBITOR AND AN ADENOSINE DEAMINASE INHIBITOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-19 | — | — | WO | disclosed |