Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 4/20 | 0.39 |
| ▸ | SPIN1 | Q9Y657 | 3/20 | 0.36 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | EBP | Q15125 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | KMT5A | Q9NQR1 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448706 | 1.00 | EHMT2 (0.39) | EHMT2SPIN1EHMT1CHEK1LMNA | |
| SCHEMBL7393975 | 0.78 | PDE4A (0.36) | LMNAALDH1A1L3MBTL1 | |
| SCHEMBL7445640 | 0.76 | HTR2A (0.38) | CHEK1HTR1A | |
| SCHEMBL7445629 | 0.76 | HTR2A (0.38) | CHEK1HTR1A | |
| SCHEMBL8344604 | 0.76 | ALDH1A1 (0.36) | CHEK1LMNAALDH1A1L3MBTL1 | |
| SCHEMBL7444417 | 0.75 | EHMT2 (0.35) | EHMT2CHEK1LMNAHTR1AADRA2A | |
| SCHEMBL7393757 | 0.75 | EHMT2 (0.35) | EHMT2CHEK1LMNAHTR1AADRA2A | |
| SCHEMBL7393752 | 0.75 | EHMT2 (0.35) | EHMT2CHEK1LMNAHTR1AADRA2A | |
| SCHEMBL7403386 | 0.74 | EHMT2 (0.36) | EHMT2CHEK1LMNAHTR1AADRA2A | |
| SCHEMBL7403389 | 0.74 | EHMT2 (0.36) | EHMT2CHEK1LMNAHTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001064648-A1 | ISOQUINOLINE DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2001-09-07 | — | — | WO | disclosed |