Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 15/20 | 0.78 |
| ▸ | NPC1 | O15118 | 15/20 | 0.78 |
| ▸ | ATM | Q13315 | 3/20 | 0.78 |
| ▸ | TP53 | P04637 | 5/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | TSHR | P16473 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.64 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.64 |
| ▸ | RELA | Q04206 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13219598 | 0.85 | RAB9A (0.66) | RAB9ANPC1ATMTP53SMN1; SMN2 | |
| SCHEMBL21788606 | 0.84 | HDAC2 (0.73) | RAB9ANPC1ATMTP53SMN1; SMN2 | |
| SCHEMBL7450576 | 0.82 | NPC1 (1.00) | RAB9ANPC1ATMTP53SMN1; SMN2 | |
| SCHEMBL14479864 | 0.82 | NPC1 (0.70) | RAB9ANPC1ATMTP53SMN1; SMN2 | |
| SCHEMBL13701152 | 0.81 | RAB9A (0.74) | RAB9ANPC1ATMTP53SMN1; SMN2 | |
| SCHEMBL7398515 | 0.80 | RAB9A (0.71) | RAB9ANPC1ATMTP53SMN1; SMN2 | |
| SCHEMBL19476104 | 0.80 | NPC1 (0.67) | RAB9ANPC1ATMTP53SMN1; SMN2 | |
| SCHEMBL7453037 | 0.80 | MAOB (0.72) | RAB9ANPC1ATMTP53SMN1; SMN2 | |
| SCHEMBL2610072 | 0.79 | NPC1 (0.78) | RAB9ANPC1ATMTP53SMN1; SMN2 | |
| SCHEMBL5866982 | 0.78 | NPC1 (1.00) | RAB9ANPC1ATMTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873331-A1 | BENZOFURAN CARBOXAMIDES AND SULPHONAMIDES | Darwin Discovery Limited (GB) | 1998-10-28 | — | — | EP | claimed |
| WO-1997020833-A1 | BENZOFURAN CARBOXAMIDES AND SULPHONAMIDES | DARWIN DISCOVERY LIMITED (GB) | 1997-06-12 | — | — | WO | claimed |