Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790845 | 0.76 | UHRF1 (0.36) | KMT2AMAPTCYP2C9ALOX15NPSR1 | |
| SCHEMBL13806057 | 0.73 | ALOX15 (0.35) | KMT2AMAPTCYP2C9ALOX15NPSR1 | |
| SCHEMBL1092751 | 0.72 | ALOX15 (0.37) | KMT2AMAPTCYP2C9ALOX15NPSR1 | |
| SCHEMBL20909664 | 0.72 | MAP4K1 (0.35) | KMT2AALOX15NPSR1NPC1RAB9A | |
| SCHEMBL27253721 | 0.72 | RXRA (0.33) | KMT2AMAPTCYP2C9ALOX15NPSR1 | |
| SCHEMBL24690690 | 0.71 | ALOX15 (0.36) | KMT2AALOX15NPSR1NPC1RAB9A | |
| SCHEMBL2632680 | 0.70 | MALT1 (0.46) | MAPTCYP2C9ALOX15NPSR1 | |
| SCHEMBL13806008 | 0.69 | IDH1 (0.33) | KMT2AALOX15NPSR1 | |
| SCHEMBL17050212 | 0.68 | KMT2A (0.34) | KMT2AALOX15NPSR1 | |
| SCHEMBL25594452 | 0.68 | EDNRB (0.35) | KMT2AMAPTCYP2C9ALOX15NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5561135-A | PSYCHOLOGICAL DISORDERS | FERRER INTERNACIONAL, S.A. (ES) | 1996-10-01 | — | — | US | claimed |
| US-5561135-A | PSYCHOLOGICAL DISORDERS | FERRER INTERNACIONAL, S.A. (ES) | 1996-10-01 | — | — | US | disclosed |
| EP-0660819-A1 | NEW N,N,N',N'-TETRASUBSTITUTED-1,2-ETHANEDIAMINE DERIVATIVE COMPOUNDS. | FERRER INT (ES) | 1995-07-05 | — | — | EP | disclosed |
| WO-1995003270-A1 | NEW N,N,N',N'-TETRASUBSTITUTED-1,2-ETHANEDIAMINE DERIVATIVE COMPOUNDS | FERRER INTERNACIONAL, S.A. (ES) | 1995-02-02 | — | — | WO | disclosed |