Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 8/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GRM8 | O00222 | 2/20 | 0.44 |
| ▸ | GRM6 | O15303 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.43 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cycloleucine SCHEMBL1704308 | 1.00 | NSD2 (0.48) | NSD2GRM4CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL15095885 | 1.00 | NSD2 (0.48) | NSD2GRM4CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL59793 | 1.00 | NSD2 (0.48) | NSD2GRM4CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL8981098 | 1.00 | NSD2 (0.48) | NSD2GRM4CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL21423145 | 1.00 | NSD2 (0.48) | NSD2GRM4CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL60473 | 1.00 | NSD2 (0.48) | NSD2GRM4CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL62221 | 1.00 | NSD2 (0.48) | NSD2GRM4CYP2C19CYP1A2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1321302 | 0.97 | NSD2 (0.46) | NSD2GRM4CYP2C19CYP1A2ALDH1A1 | |
| Methane SCHEMBL11142076 | 0.97 | NSD2 (0.46) | NSD2GRM4CYP2C19CYP1A2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL21497076 | 0.97 | NSD2 (0.46) | NSD2GRM4CYP2C19CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658885-A | OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-19 | — | — | US | claimed |
| US-20200360483-A1 | METHOD FOR INHIBITING INFLAMMATION and PRO-INFLAMMATORY CYTOKINE/CHEMOKINE EXPRESSION USING A GHRELIN ANALOGUE | IPSEN PHARMA S.A.S. (FR) | 2020-11-19 | — | — | US | disclosed |
| US-20200347110-A1 | Composition and Methods for Stimulating Gastrointestinal Motility | IPSEN PHARMA S.A.S. (FR) | 2020-11-05 | — | — | US | disclosed |
| EP-3481828-B1 | SPIRO-FUSED CYCLIC UREAS AS INHIBITORS OF ROCK | BRISTOL MYERS SQUIBB CO (US) | 2020-09-16 | — | — | EP | disclosed |
| US-20190248861-A1 | Composition and Methods for Stimulating Gastrointestinal Motility | IPSEN PHARMA S.A.S. (FR) | 2019-08-15 | — | — | US | disclosed |
| EP-1937262-B1 | COMPOSITION FOR USE IN TREATING GASTROINTESTINAL DYSMOTILITY | IPSEN PHARMA (FR) | 2019-05-08 | — | — | EP | disclosed |
| CN-105381453-B | Composition and method for stimulating gastrointestinal motility | 益普生制药股份有限公司 | 2018-11-13 | — | — | CN | disclosed |
| US-20170304403-A1 | METHOD FOR INHIBITING INFLAMMATION and PRO-INFLAMMATORY CYTOKINE/CHEMOKINE EXPRESSION USING A GHRELIN ANALOGUE | IPSEN PHARMA S.A.S. (FR) | 2017-10-26 | — | — | US | disclosed |
| US-20170037104-A1 | Composition and Methods for Stimulating Gastrointestinal Motility | IPSEN PHARMA S.A.S. (FR) | 2017-02-09 | — | — | US | disclosed |
| US-9499599-B2 | Composition and methods for stimulating gastrointestinal motility | IPSEN PHARMA S.A.S. (FR) | 2016-11-22 | — | — | US | disclosed |
| WO-2000034332-A1 | GLP-1 ANALOGUES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES SAS (FR) | 2000-06-15 | — | — | WO | disclosed |
| WO-2000005260-A1 | PEPTIDE ANALOGUES OF PACAP | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES SAS (FR) | 2000-02-03 | — | — | WO | disclosed |
| WO-1999057139-A2 | PTH2 RECEPTOR SELECTIVE COMPOUNDS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES SAS (FR) | 1999-11-11 | — | — | WO | disclosed |
| EP-0948541-A2 | ANALOGS OF PARATHYROID HORMONE | Biomeasure Incorporated (US) | 1999-10-13 | — | — | EP | disclosed |
| US-5955574-A | POLYPEPTIDES FROM AMINO ACIDS AND PRODUCED BY PARATHYROID GLANDS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A. (FR) | 1999-09-21 | — | — | US | disclosed |
| WO-1998030590-A9 | ANALOGS OF PARATHYROID HORMONE | BIOMEASURE INC (US) | 1999-08-19 | — | — | WO | disclosed |
| WO-1998030590-A2 | ANALOGS OF PARATHYROID HORMONE | BIOMEASURE INCORPORATED (US) | 1998-07-16 | — | — | WO | disclosed |
| US-5658885-A | OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-19 | — | — | US | disclosed |
| US-5543414-A | VIRICIDES | SYNTEX (USA) INC. (US) | 1996-08-06 | — | — | US | disclosed |
| WO-1996012499-A1 | AMIDINO AND GUANIDINO SUBSTITUTED INHIBITORS OF TRYPSIN-LIKE ENZYMES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-05-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170304403-A1 | METHOD FOR INHIBITING INFLAMMATION and PRO-INFLAMMATORY CYTOKINE/CHEMOKINE EXPRESSION USING A GHRELIN ANALOGUE | PROKR1, CCL2, PROKR2 | NSD2 4201/4885GRM4 341/4885CYP2C19 3695/4885 |
| US-20170037104-A1 | Composition and Methods for Stimulating Gastrointestinal Motility | GIPR, VIP, GRPR | NSD2 4546/4885GRM4 524/4885CYP2C19 2816/4885 |
| US-20200360483-A1 | METHOD FOR INHIBITING INFLAMMATION and PRO-INFLAMMATORY CYTOKINE/CHEMOKINE EXPRESSION USING A GHRELIN ANALOGUE | PROKR1, CCL2, PROKR2 | NSD2 4201/4885GRM4 341/4885CYP2C19 3695/4885 |
| US-20190248861-A1 | Composition and Methods for Stimulating Gastrointestinal Motility | GIPR, VIP, GRPR | NSD2 4546/4885GRM4 524/4885CYP2C19 2816/4885 |
| US-20200347110-A1 | Composition and Methods for Stimulating Gastrointestinal Motility | GIPR, VIP, GRPR | NSD2 4546/4885GRM4 524/4885CYP2C19 2816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.